Orthopoxvirus and monkeypox coding & guidance


New Current Procedural Terminology (CPT®) codes have been created that streamline the reporting of orthopoxvirus and monkeypox testing and immunizations currently available on the United States market.

The CPT Editorial Panel has approved addition of code 87593 to report orthopoxvirus detection by nucleic acid using amplified probe technique.

87593:    Infectious agent detection by nucleic acid (DNA or RNA); orthopoxvirus (e.g., monkeypox virus, cowpox virus, vaccinia virus), amplified probe technique, each

Review and download the full CPT code descriptor release.

The CPT Editorial Panel has approved addition of accepted addition of code 90622 to identify vaccinia (smallpox) virus vaccine product; and addition of code 90611 to identify monkeypox and smallpox virus vaccine product.

90611:    Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use

90622:    Vaccinia (smallpox) virus vaccine, live, lyophilized, 0.3 mL dosage, for percutaneous use

Category I vaccine descriptors immunizations

Please visit the early release page for additional information on Category I codes.

CPT Assistant provides fact sheets for coding guidance for new related orthopoxvirus and monkeypox testing and immunization codes.

Access additional AMA content about monkeypox and smallpox.

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