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In
reviewing Rebecca's family history (click
here for full pedigree/family history tree)
it becomes clear that in addition to her mother who
was diagnosed with breast cancer at 40 and her maternal
aunt who was diagnosed with breast cancer at 37, Rebecca's
grandmother died of a "female cancer" in her
40's.
You discuss that this could have been ovarian
cancer (NCI link) but that it cannot be confirmed
without medical records.
Based on her family history, you review autosomal
dominant (NHGRI definition) inheritance with Rebecca
and discuss what family members may be at risk for developing
breast and/or ovarian cancer.
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