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Two
cancer susceptibility genes, BRCA1 and BRCA2,
have been identified for hereditary breast and ovarian
cancer. As a consequence of the availability of genetic
tests for mutations in these two genes, physicians should
become knowledgeable about the appropriate use of these
tests, in the context of patient selection, the information
gained from such tests, management of clinical risk
for cancer and the need for effective pre- and post-test
patient counseling. Thus physicians need educational
programs that provide an introduction to hereditary
breast and ovarian cancer, available genetic tests,
appropriate circumstances for testing, rationale for
detailed family cancer history, and the requirement
for patient education and counseling.
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