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Stem-cell research potential tempered by ethical issues

Embryonic stem cells may be the new kids on the block, but their promising attributes are attracting much attention.

By Susan J. Landers, amednews staff. Aug. 13, 2001.

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Washington -- Regardless of whether stem-cell research moves forward with embryonic stem cells or adult stem cells, with public or private funding, recent results have sparked enough enthusiasm, controversy and debate to carry the field forward for a long time.

If stem cells live up to their promise, they could dramatically improve physicians' odds of defeating a long list of serious conditions that include diabetes, Parkinson's disease, end-stage kidney disease, liver failure, heart disease, multiple sclerosis, spinal cord injury and stroke.

But, the promise of embryonic stem cells is not only a long way from being realized, it is also tempered by problematic ethical issues.

Meanwhile, the difficulties of working with adult stem cells has dimmed researchers' zeal.

Still, the potential of stem-cell research can be tantalizing.

"Over 3,000 people die every day in the United States from diseases that may someday be treatable as a result of stem-cell research," according to a report by the Progressive Policy Institute, a Washington, D.C.,-based think tank.

While much of the recent interest has been sparked by embryonic stem cells, which were first isolated from embryos only three years ago, the momentum for research on adult stem cells, which has been conducted for many years, has waned a bit.

Much remains unknown. "So far, adult stem cells have proven to be very different from embryonic stem cells," ventures Tony Mazzaschi, associate vice president for research at the American Assn. of Medical Colleges. He notes that the AAMC supports research on both types of stem cells. The AMA also strongly supports all stem-cell research, as do numerous other medical groups. [...]