Virus linked to ALS for first time
Irvine, Calif. -- The finding of a virus in the spinal cords of patients with amyotrophic lateral sclerosis provides the best evidence of a possible viral cause of Lou Gehrig's disease, according to researchers at the University of California, Irvine, and in Lyon, France.
Researchers found that 15 of 17 patients with ALS showed evidence of a virus in the motor nerve cells of their spinal cords, while the virus was found in only one of 29 people who died of other causes.
Many researchers have long suspected a viral link to ALS, "but in this study we were able to identify a virus known for nerve damage in the exact areas of the nervous system that are affected by this disease," said Martina Berger, a UCI researcher.
The researchers used a highly sensitive technique, reverse-transcriptase polymerase chain reaction, to detect the presence of the virus using trace amounts of its genetic material. The researchers' findings are reported in the January issue of Neurology.
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