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Genetics and Molecular Medicine


Few areas of medicine hold as much promise or controversy as that focused on what happens in our bodies at the molecular level.

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Genetic testing news

EGAPP releases recommendation statement on genetic testing in patients beginning SSRI therapy

The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group found insufficient evidence to recommend the use of cytochrome P450 (CYP450) testing in patients beginning treatment with SSRIs. The full recommendation statement appears in the December 2007 issue of Genetics in Medicine and is freely accessible through the EGAPP Working Group Web site.

Carbemazepine prescribing information to include recommendation of genetic tests for patients with Asian ancestry

Dec. 12, 2007 - The U.S. Food and Drug Administration today announced that the manufacturers of drugs containing the active ingredient carbamazepine have agreed to add to the drugs' labeling a recommendation that, before starting therapy with the drugs, patients with Asian ancestry get a genetic blood test that can identify a significantly increased risk of developing a rare, but serious, skin reaction. For further information, read the FDA announcement.

Warfarin labeling revised by the FDA

Aug. 16, 2007 - The U.S. Food and Drug Administration today released revised labeling for the drug warfarin.  The revised labeling includes information on the influence of genetics on warfarin dosing. View (PDF, 34KB) a description of the labeling revision and other information on genetic testing available to aid in warfarin dosing.

Last updated: Mar 05, 2008
Content provided by: AMA Science


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